産品信息
| 規格 | 100μg/支 |
| 貨号 | Gab-202207 |
| 反應物種 | Human |
| 産品應用 | 測試種屬及綜合評分 |
| 推薦稀釋比 | WB 1:500 - 1:2000 |
| IHC 1:50 - 1:200 | |
| IF 1:50 - 1:200 | |
| IP 1:50 - 1:200 | |
| 理(lǐ)論分子(zǐ)量 | 58kDa |
| 實際分子(zǐ)量 | 60kDa |
| 存儲緩沖液 | Store at -20℃. Avoid freeze / thaw cycles. |
| Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. | |
| 陽性樣本 | HeLa,293T,SH-SY5Y |
| 細胞定位 | Nucleus,Nucleus speckle |
| 純化方式 | Affinity purification |
抗原信息
| 免疫原 | A synthesized peptide derived from human FTO |
| 序列 | Email for sequence |
靶點背景信息
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]
| RRID | AB_2863150 |
| 基因ID | 79068 |
| Swiss Prot | Q9C0B1 |
| 别名 | ALKBH9; BMIQ14; GDFD |
